Anemia… MCQ – Microcytic Anaemia 3 Apr 20193 Apr 2019 1. Which of the following diagnosis can be excluded by the presence of microcytosis Aplastic anaemia Iron deficiency Paroxysmal nocturnal haemoglobinuria Sideroblastic anaemia 2. Which of the following are true…
Erythropoiesis… Regulation of Haematopoiesis 23 Mar 2019 All blood cells arise from the haemaopoietic stem cell. The path along which the stem cell progeny matures is dictated by the needs of the body. Examples of this include…
Multiple Choice Questions Multiple Choice Questions -1 22 Mar 201922 Mar 2019 1. A 45 year old male patient presents with eosinophilia and fever. Which of the following diagnosis is unlikely. Hodgkin lymphoma Typhoid fever Chronic Myeloid leukaemia Polyarteritis nodosa 2. 62 year…
Follicular Lymphoma… Follicular Lymphoma – Epidemiology 3 Aug 201816 Mar 2019 Follicular lymphoma (FL) is one of the most common types of non-hodgkin lymphoma. Its incidence is second to only diffuse large B cell lymphoma. It is slightly more common in…
Anaemia of Renal Insufficiency… Clinical Features of Multiple Myeloma 10 Jun 201810 Jun 2018 Myeloma causes symptoms by infiltration, production of paraproteins and production of cytokines. The common manifestations include anemia, bone pain, renal impairment, fatigue and weight loss, hypercalcaemia, and neurological manifestations. Anaemia…
Disease Monograph… Febrile Non-Haemolytic Transfusion Reaction 8 Jun 2018 Febrile non-haemolytic transfusion reaction (FNHTR) is the most common transfusion reaction. Its needs to be differentiated from haemolytic transfusion reaction and bacterial contamination both of which are serious and potentially…
Coagulation Disorders… Factor VII 7 Jun 2018 Factor VII is a vitamin K dependent coagulation factor. It is a serine protease. Activation of factor VII is the first step in the coagulation cascade. Deficiency is rare and…
Anti-coagulants… Vitamin K 6 Jun 20186 Jun 2018 Vitamin K was discovered by Henrik Dam in 1929 while studying cholesterol metabolism in chicken (see Discovery of Vitamin K and It's Targets and Antagonists). It is a co-factor for post translation…
Lymphoma… Marginal Zone Lymphoma 25 Apr 201825 Apr 2018 Marginal zone lymphomas are low grade lymphoma that are believed to arise from the lymphocytes of the marginal zone of lymphoid follicles. The marginal zone lies outside the mantle zone.…
Anemia… Treatment of Warm Antibody Type Autoimmune Haemolytic Anaemia (WAIHA) 20 Feb 201820 Feb 2018 Warm antibody type of autoimmune haemolytic anaemia (WAIHA) is characterised by anaemia, reticulocytosis, conjugated hyperbilirubinaemia with the presence of a positive anti-globulin (Coombs') test (see Diagnosis of haemolytic anaemia). It may…
