Large Granular Lymphocyte

Typically lymphocytes are small (10-12μm) cells with a scanty agranular cytoplasm with a round slightly indented nucleus. About 10% of lymphocytes are larger (12-16μ), have a nucleus which has a slight less compact chromatin and azurophilic granules in the cytoplasm. These are known as large granular lymphocytes. Some of these are T supressor lymphocytes (Cd3+ Cd8+) while others are NK cells (Cd3 – CD8+). The picture above shows a large granular lymphocyte.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

w

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.